Luckily there is a lot more processing of CBD happening around the world so that people can make ingestion decisions that fit their lifestyle or medical need. Here is a breakdown of the most common ingestions methods for CBD.
Types: CBD oil, tinctures, edibles, capsules, powder
Pathway to targets: When CBD is ingested, it passes through the digestive tract, where it’s absorbed into the bloodstream and travels throughout your body.
Time-frame: This is the slowest route for CBD to reach its targets, but also the longest period of time that it’s active. Peak bloodstream levels are reported anywhere between 1-6 hours. Best for long-term supplementation.
Types: CBD oil, tinctures, tablets
Pathway to targets: CBD can be absorbed directly into your bloodstream from capillary-rich areas underneath the tongue, along the gums and cheek. From here, it avoids first-pass metabolism and is sent throughout your body.
Time-frame: This route gets CBD into your bloodstream faster than swallowing. Under the tongue (sublingual) is generally quicker than against the cheek (buccal). However, because most of the CBD will eventually be swallowed, peak bloodstream levels range from 0.5 – 5 hours.
Types: Vape pens, dabs, high-CBD cannabis
Pathway to targets: When CBD is inhaled, it passes to the lungs where it rapidly passes into the bloodstream. Inhalation avoids first-pass metabolism.
Time-frame: This is the quickest way to get CBD circulating through your system, but it also is effective for the shortest period of time. Peak bloodstream levels are within 10 minutes.
Types: Creams, lotions, salves
Pathway to targets: Topical CBD diffuses across your skin and reaches local targets, like muscles, inflammatory cells, and pain-perceiving nerves. Very little, if any, enters the bloodstream — unless it is designed for transdermal activity.
Time-frame: Varies, depending on the target.
Everything we’ve been discussing — the pharmacokinetics of cannabidiol — is a complicated subject that scientists are still actively piecing together. There are no established guidelines for the best way to use CBD to achieve your health goals. Prepare for a truly unique experience that deserves patient and loving experimentation. We wish you success on your journey!